Assay
Age
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Immunohistochemistry (whole mount)
Postnatal
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Phox2b paired-like homeobox 2b (Synonyms: Dilp1, GENA 269, NBPhox, Phox2b, Pmx2b, Px2b) | |
Results | Reference |
1* | J:132978 Corpening JC, Cantrell VA, Deal KK, Southard-Smith EM, A Histone2BCerulean BAC transgene identifies differential expression of Phox2b in migrating enteric neural crest derivatives and enteric glia. Dev Dyn. 2008 Apr;237(4):1119-32 |
1 | J:308534 Okamoto M, Uesaka T, Ito K, Enomoto H, Increased RET Activity Coupled with a Reduction in the RET Gene Dosage Causes Intestinal Aganglionosis in Mice. eNeuro. 2021 May-Jun;8(3):ENEURO.0534-20.2021 |
1 | J:275428 Okamoto M, Yoshioka Y, Maeda K, Bito Y, Fukumoto T, Uesaka T, Enomoto H, Mice conditionally expressing RET(C618F) mutation display C cell hyperplasia and hyperganglionosis of the enteric nervous system. Genesis. 2019 May;57(5):e23292 |
1 | J:224366 Uesaka T, Nagashimada M, Enomoto H, Neuronal Differentiation in Schwann Cell Lineage Underlies Postnatal Neurogenesis in the Enteric Nervous System. J Neurosci. 2015 Jul 8;35(27):9879-88 |
1 | J:320743 Uesaka T, Okamoto M, Nagashimada M, Tsuda Y, Kihara M, Kiyonari H, Enomoto H, Enhanced enteric neurogenesis by Schwann cell precursors in mouse models of Hirschsprung disease. Glia. 2021 Nov;69(11):2575-2590 |
1 | J:165146 Walters LC, Cantrell VA, Weller KP, Mosher JT, Southard-Smith EM, Genetic background impacts developmental potential of enteric neural crest-derived progenitors in the Sox10Dom model of Hirschsprung disease. Hum Mol Genet. 2010 Nov 15;19(22):4353-72 |
1 | J:57952 Young HM, Ciampoli D, Hsuan J, Canty AJ, Expression of Ret-, p75(NTR)-, Phox2a-, Phox2b-, and tyrosine hydroxylase-immunoreactivity by undifferentiated neural crest-derived cells and different classes of enteric neurons in the embryonic mouse gut. Dev Dyn. 1999 Oct;216(2):137-52 |
1 | J:50258 Young HM, Hearn CJ, Ciampoli D, Southwell BR, Brunet JF, Newgreen DF, A single rostrocaudal colonization of the rodent intestine by enteric neuron precursors is revealed by the expression of Phox2b, Ret, and p75 and by explants grown under the kidney capsule or in organ culture. Dev Biol. 1998 Oct 1;202(1):67-84 |
1 | J:316159 Yu Q, Du M, Zhang W, Liu L, Gao Z, Chen W, Gu Y, Zhu K, Niu X, Sun Q, Wang L, Mesenteric Neural Crest Cells Are the Embryological Basis of Skip Segment Hirschsprung's Disease. Cell Mol Gastroenterol Hepatol. 2021;12(1):1-24 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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